Cosmetic in Japan 美容医学への扉-東京大学美容外科-アンチエイジング
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Web Master -Kotaro Yoshimura, M.D.-


Department of Plastic Surgery, University of Tokyo, Tokyo, Japan

Department of Plastic Surgery, University of Tokyo School of Medicine,
7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Phone: +813-5800-8948
Fax: +813-5800-8947

Publication web:

Maps to the office






Graduated from the University of Tokyo School of Medicine in 1985, and entered the Department of Plastic Surgery, University of Tokyo.
Associate doctor, Department of Plastic Surgery, University of Tokyo from 1990 to 1998.
Visiting researcher, Department of Plastic Surgery, University of Michigan from 1994 to 1995.
Associate professor, Department of Plastic Surgery, University of Tokyo since 1998.
2006-: Visiting professor, Department of Department of Plastic Surgery, Kyorin University (Tokyo)
2009, Visiting Professor of the Division of Plastic and Reconstructive Surgery at Cedars Sinai Medical Center
2009, Visiting Professor of the Division of Plastic and Reconstructive Surgery at University of California Davis

A member of the board and the Academic Comittee of Japanese Society of Plastic & Reconstructive Surgery (JSPRS)
A Corresponding Member of American Society of Plastic Surgery (ASPS). (ASPS member#: 31317).
A Corresponding Member of American Society of Aesthtic Plastic Surgery (ASAPS). (ASPS member#: 31317).
A member of International Society of Plastic and Recosntructive Surgery (IPRAS)
A member of International Society of Aesthtic Plastic Surgery (ISAPS)


If you have any questions, concerns, or any other issues, please feel free to contact me.
If you are interested in undergoing surgery such as Cell-Assisted Lipotransfer, please feel free to contact me.

Publications (only peer-reviewed international journals)

1) Sugawara Y, Hirabayashi S, Asato H, Yoshimura K. Reconstruction of the umbilicus using a single triangular flap. Ann Plast Surg 34: 78-80, 1995. [PDF]
2) Yoshimura K, Faulkner JA, Kuzon WM. Influence of skeletal muscle architecture on contractile properties after tenotomy or myotomy. Surgical Forum 46: 603-605, 1995.
3) Asato H, Harii K, Nakatsuka T, Yoshimura K. Use of the disposable stapler to insure proper fixation of a transferred muscle in treatment of facial paralysis. J Reconstr Microsurg 19: 199-204, 1998. [PDF]
4)* Yoshimura K, Kuzon WM, Harii K. Myosin heavy chain expression in skeletal muscle autografts under neural or aneural condition.J Surg Res 75: 135-147, 1998. [PDF]
5)* Yoshimura K, Harii K, Asato H, Ueda K, Yamada A. Immunohistochemical study of clinically transplanted muscles.J Surg Res 79: 31-38, 1998. [PDF]
6)* Yoshimura K, Nakatsuka T, Ichioka S, Kaji N, Harii K. One-stage reconstruction of an upper part defect of the auricle.Aesth Plast Surg, 22: 352-355, 1998. [PDF]
7) Ueda K, Harii K, Asato H, Yoshimura K, Yamada A. Evaluation of muscle graft using facial nerve on the affected side as a motor source in the treatment of facial paralysis. Scand J Plast Reconstr Surg Hand Surg, 33: 47-57, 1998. [PDF]
8) Harii K, Asato H, Yoshimura K, Sugawara Y, Nakatsuka T, Ueda K. One-stage transfer of the latissimus dorsi muscle for the reanimation of a paralyzed face. Plast Reconstr Surg, 102: 941-951, 1998. [PDF]
9)* Yoshimura K, Harii K. A regenerative change during muscle adaptation to denervation in rats. J Surg Res 81: 139-146, 1999. [PDF]
10)* Yoshimura K, Harii K, Aoyama T, Shibuya F, Iga T. A new bleaching protocol for hyperpigmented skin lesions with a high concentration of all-trans retinoic acid aqueous gel. Aesth Plast Surg, 23: 285-291, 1999. [PDF]
11) Nakatsuka T, Harii K, Takushima A, Yoshimura K, Ichioka S, Sugasawa M, Ichimura K, Seto Y, Nagawa H. Prefabricated free jejunal transfer: a new reconstructive technique for high pharyngeal defects. Plast Reconstr Surg, 103: 458-464, 1999. [PDF]
12) Ichioka S, Nakatsuka T, Yoshimura K, Kaji N, Harii K. Free jejunal patch to reconstruct oral scar contracture following caustic ingestion. Ann Plast Surg 43: 83-86, 1999. [PDF]
13) Yoshimura K, Asato H, Cederna PS, Urbanchek MG, Kuzon WM. The effect of reinnervation on force production and power output in skeletal muscle. J Surg Res 81: 201-208, 1999. [PDF]
14)* Yoshimura K, Asato H, Nakatsuka T, Sugawara Y, Park S. Elevation of a constructed auricle using the anteriorly-based mastoid fascial flap. Brit J Plast Surg 52: 530-533, 1999. [PDF]
15)* Kawasaki Y, Yoshimura K, Harii K, Park S. Identification of motor and sensory axons in a regenerating mixed nerve. J Hand Surg (Am) 25A: 104-111, 2000. [PDF]
16)* Yoshimura K, Harii K, Aoyama T, Iga T. Experience of a Strong Bleaching Treatment for Skin Hyperpigmentation in Orientals. Plast Reconstr Surg, 105: 1097-1110, 2000. [PDF]
17)* Yoshimura K, Ouchi K, Wakita S, Uda K, Harii K. Surgical correction of cryptotia with superiorly-based superficial mastoid fascia and skin paddle. Plast Reconstr Surg, 105: 836-841, 2000. [PDF]
18) Gonda K, Nakaoka T, Yoshimura K, Otawara-Hamamoto Y, Harii K. Heterotopic ossification of degenerating rat skeletal muscle induced by adenovirus-mediated transfer of bone morphogenetic protein-2 gene. J Bone Mine Res 15: 1056-1065, 2000. [PDF]
19)* Yoshimura K, Tsukamoto K, Okazaki M, Virador VM, Lei TC, Suzuki Y, Uchida G, Kitano Y, Harii K. Effects of all-trans retinoic acid on melanogenesis in pigmented skin equivalents and monolayer culture of melanocytes J Dermatol Sci, 27(S1): 68-75, 2001. [PDF]
20) Kitano Y, Yoshimura K, Uchida G, Sato K, Harii K. Wound healing of genetically diabetic mouse after topical treatment with all-trans retinoic acid. Arch Dermatol Res. 292:515-521, 2001. [PDF]
21)* Yoshimura K, Harii K, Masuda Y, Takahashi M, Aoyama T, Iga T: Usefulness of a narrow-band reflectance spectrophotometer in evaluating effects of depigmenting treatment. Aesth Plast Surg, 25: 129-33, 2001. [PDF]
22) Park S, Iida T, Yoshimura K, Harii K. Phenol cauterization for ganglions of the hand, wrist, and foot: a preliminary report. Ann Plast Surg, 48:582-585, 2002. [PDF]
23) Yoshimura K, Asato H, Jejurikar SS, Cederna PS, Urbanchek MG, Kuzon WM. The effect of two episodes of denervation and reinnervation on skeletal muscle contractile function. Plast Reconstr Surg. 109:212-219, 2002. [PDF]
24) Okazaki M, Yoshimura K, Uchida G, Harii K. Elevated expression of Hepatocyte and Keratinocyte Growth Factor in cultured buccal-mucosa-derived fibroblasts compared with normal-skin-derived fibroblasts. J Dermatol Sci, 30: 108-115, 2002. [PDF]
25)* Yoshimura K, Momosawa A, Watanabe A, Sato K, Matsumoto D, Aiba E, Harii K, Yamamoto T, Aoyama T, Iga T. Cosmetic color improvement of the nipple-areola complex by optimal use of tretinoin and hydroquinone. Dermatol Surg 28:1153-1157, 2002. [PDF]
26) Okazaki M, Yoshimura K, Fujiwara H, Suzuki Y, Harii K. Induction of hard keratin in non-nail-matrical keratinocytes by nail-matrical fibroblasts through epithelial-mesenchymal interaction. Plast Reconstr Surg 111: 286-290, 2003. [PDF]
27)* Yoshimura K, Momosawa A, Aiba E, Sato K, Matsumoto D, Mitoma Y, Harii K, Aoyama T, Iga T. Clinical trial of bleaching treatment with 10% all-trans retinol gel. Dermatol Surg 29: 155-160, 2003. [PDF]
28) Okazaki M, Yoshimura K, Suzuki Y, Uchida G, Kitano Y, Harii K, Imokawa G. The mechanism of epidermal hyperpigmentation in cafe-au-lait macules of neurofibromatosis type 1 (von Recklinghausen's disease) may be associated with dermal fibroblast-derived stem cell factor and hepatocyte growth factor. Brit J Dermatol 148: 689-697, 2003. [PDF]
29)* Uchida G, Yoshimura K, Kitano Y, Okazaki M, Harii K. Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts. Exp Dermatol, 12(Suppl.2): 35-42, 2003. [PDF]
30)* Yoshimura K. Uchida G. Okazaki M. Kitano Y. Harii K. Differential expression of heparin-binding EGF-like growth factor (HB-EGF) mRNA in normal human keratinocytes induced by a variety of natural and synthetic retinoids. Exp Dermatol, 12(Suppl.2): 28-34, 2003. [PDF]
31)* Momosawa A, Yoshimura K, Uchida G, Sato K, Aiba E, Matsumoto D, Mihara S, Tsukamoto K, Harii K, Aoyama T, Iga T. Combined Therapy Using Q-Switched Ruby Laser and Bleaching Treatment with Tretinoin and Hydroquinone for Acquired Dermal Melanocytosis. Dermatol Surg, 29: 1001-1007, 2003. [PDF]
32) Okazaki M, Yoshimura K, Suzuki Y, Harii K. Subepithelial fibroblasts influence on epithelial differentiations in human skin and oral mucosa: Heterotypically recombined organotypic culture model. Plast Reconstr Surg, 112: 784-92, 2003. [PDF]
34) Hirohi T, Yoshimura K. Surgical Correction of Retracted Nostril Rim with Auricular Composite Grafts and Anchoring Suspension. Aesth Plast Surg, 27: 418-422, 2003. [PDF]
35)* Yoshimura K, Wakita S, Sato K, Kaji N, Aiba E, Matsumoto D, Yamaoka H, Nagase T. A Clinical trial of Simultaneous Reconstruction of Breast and Well-Projected Nipple Following Expansion of Breast Skin. Scand J Plast Reconstr Surg Hand Surg, 39: 77-84, 2005. [PDF]
36)* Nagase T, Yoshimura K, Aiba E, Matsumoto D, Sato K, Machino C. Angle-splitting Ostectomy Followed by Facelift for Elderly Patients with Prominent Mandibular Angles. Plast Reconstr Surg, 115: 633-40, 2005. [PDF]
37) Okazaki M, Yoshimura K, Uchida G, Suzuki Y, Kitano Y, Harii K. Epidermal hyperpigmentation in non-syndromic solitary cafe-au-lait macules may be associated with increased secretion of endothein-1 by lesional keratinocytes. Scand J Plast Reconstr Surg Hand Surg, 39: 213-217, 2005. [PDF]
38) Okazaki M, Yoshimura K, Uchida G, Harii K. Correlation between age and the secretions of melanocyte-stimulating cytokines in cultured keratinocytes and fibroblasts. Brit J Dermatol, 153(Suppl 2): 23-29, 2005. [PDF]
39) Nagase T, Nagase M, Osumi N, Fukuda S, Nakamura S, Ohsaki K, Harii K, Asato H, Yoshimura K. Craniofacial Anomalies of the Cultured Mouse Embryo Induced by Inhibition of Sonic Hedgehog Signaling: An Animal Model of Holoprosencephaly. Journal of Craniofacial Surgery 16: 80-88, 2005. [PDF]
40 ) Nagase T, Nagase M, Yoshimura K, Fujita T, Koshima I. Angiogenesis within the developing mouse neural tube is dependent on sonic hedgehog signaling: possible roles of motor neurons. Genes Cells 10: 595-604, 2005. [PDF]
41) Mochizuki Y, Ojima K, Uezumi A, Masuda S, Yoshimura K, Takeda S. Participation of bone marrow-derived cells in fibrotic changes in denervated skeletal muscle. Am J Pathol 166: 1721-1732, 2005. [PDF]
42) Okazaki M, Suzuki Y, Yoshimura K, Harii K. Construction of pigmented skin equivalent and its application to the study of congenital disorders of pigmentation. Scand J Plast Reconstr Surg Hand Surg, 39: 339-43, 2005. [PDF]
43)* Kurita M, Aiba E, Matsumoto D, Sato K, Nagase T, Yoshimura K. Feminizing genitoplasty for treatment of XX male with masculine genitalia: case report. Plastic Reconstr Surg 117: 107e-111e, 2006. [PDF]
44)* Yoshimura K, Sato K, Aiba-Kojima E, Matsumoto D, Machino C, Nagase T, Gonda K, Koshima I. Repeated treatment protocols for Melasma and Acquired Dermal Melanocytosis. Dermatol Surg, 32: 365-371, 2006. [PDF]
45)* Yoshimura K, Shigeura T, Matsumoto D, Sato T, Takaki Y, Aiba-Kojima E, Sato K, Inoue K, Nagase T, Koshima I, Gonda K. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J Cell Physiol, 208: 64-76, 2006. [PDF]
46) Yoshimura K, DeMeester J, Hasan JS, Urbanchek MG, Kuzon WM Jr. Neurovascular Transfer Does Not Cause Skeletal Muscle Fiber Degeneration. Plastic Reconstr Surg, 117:1455-1461, 2006. [PDF]
47) Nagase T, Nagase M, Yoshimura K, Machida M, Yamagishi M. Defects in aortic fusion and craniofacial vasculature in holoprosencephalic mouse embryo under inhibision of sonic hedgehog signaling. J Craniofac Surg 17: 737-744, 2006. [PDF]
48) Koshima I, Urushibara K, Fukuda N, Ohkochi M, Nagase T, Gonda K, Asato H, Yoshimura K. Digital artery perforator flaps for fingertip reconstructions. Plast Reconstr Surg 118: 1579-84, 2006. [PDF]
49)* Sato K, Matsumoto D, Aiba-Kojima E, Machino C, Watanabe-Ono A, Inoue K, Iizuka F, Gonda K, Yoshimura K. Anti-androgenic therapy using oral spironolactone for acne vulgaris in Asians. Aesthet Plast Surg 30: 689-694, 2006. [PDF]
50 )* Matsumoto D, Sato K, Gonda K, Takaki Y, Shigeura T, Sato T, Aiba-Kojima E, Iizuka F, Inoue K, Suga H, Yoshimura K. Cell-assisted lipotransfer (CAL): supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection. Tissue Eng, 12: 3375-3382, 2006. [PDF]
51) Nagase T, Matsumoto D, Nagase M, Yoshimura K, Shigeura T, Inoue M, Hasegawa M, Yamagishi M, Machida M. Neurospheres from human adipose tissue transplanted into cultured mouse embryos can contribute to craniofacial morphogenesis: A preliminary report. J Craniofac Surg 18: 49-53, 2007. [PDF]
52)* Aiba-Kojima E, Tsuno NH, Inoue K, Matsumoto D, Sato K, Shigeura T, Sato T, Suga H, Nagase T, Gonda K, Koshima I, Takahashi K, Yoshimura K. Characterization of wound drainage fluids as a source of soluble factors associated with wound healing: comparison to platelet-rich plasma and potential use for cell-based therapies. Wound Repair Regen 15: 511-520, 2007. [PDF]
53)* Sato K, Matsumoto D, Iizuka F, Aiba-Kojima E, Machino C, Suga H, Watanabe-Ono A, Inoue K, Gonda K, Yoshimura K. A clinical trial of topical bleaching treatment with nanoscale tretinoin particles and hydroquinone for hyperpigmented skin lesions. Dermatol Surg 33: 937-944, 2007. [PDF]
54)* Suga H, Shigeura T, Matsumoto D, Inoue K, Kato H, Aoi N, Murase S, Sato K, Gonda K, Koshima I, Yoshimura K. Rapid expansion of human adipose-derived stromal cells preserving multipotency. Cytotherapy 9: 738-745, 2007. [PDF]
55)*Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K. Cell-assisted lipotransfer (CAL) for cosmetic breast augmentation -supportive use of adipose-derived stem/stromal cells-. Aesthetic Plast Surg, 32: 48-55, 2008. [PDF].
56)* Inoue K, Sato K, Matsumoto D, Gonda K, Yoshimura K. Arterial embolization and skin necrosis of the nasal ala following injection of dermal fillers. Plast Reconstr Surg, 121: 127e-128e, 2008. [PDF]
57)* Matsumoto D, Shigeura T, Sato K, Inoue K, Suga H, Iizuka F, Aoi N, Murase S, Gonda K, Yoshimura K. Influences of preservation at various temperatures on liposuction aspirates. Plast Reconstr Surg 120: 1510-1517, 2007. [PDF]
58)* Gonda K, Shigeura T, Sato T, Matsumoto D, Suga H, Inoue K, Aoi N, Iizuka F, Sato K, Murase S, Koshima I, Yoshimura K. Preserved proliferative capacity and multipotency of human adipose-derived stem cells after long-term cryopreservation. Plast Reconstr Surg 121: 401-410, 2008. [PDF]
59)* Yoshimura K, Sato K, Aoi N, Kurita M, Inoue K, Suga H, Eto H, Kato H, Hirohi T, Harii K. Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells. Dermatol Surg 34: 1178-1185, 2008. [PDF]
60)* Kurita M, Matsumoto D, Shigeura T, Sato K, Gonda K, Harii K, Yoshimura K. Influences of centrifugation on cells and tissues in liposuction aspirates: optimized centrifugation for lipotransfer and cell isolation. Plast Reconstr Surg, 121: 1033-1041, 2008. [PDF]
61)* Suga H, Matsumoto D, Inoue K, Shigeura T, Eto H, Aoi N, Kato H, Abe H, Yoshimura K. Numerical measurement of viable and non-viable adipocytes and other cellular components in aspirated fat tissue. Plast Reconstr Surg 122: 103-114, 2008. [PDF]
62)* Kurita M, Aiba-Kojima E, Shigeura T, Matsumoto D, Suga H, Inoue K, Eto H, Kato H, Aoi N, Yoshimura K. Differential effects of three preparations of human serum on expansion of various types of human cells. Plast Reconstr Surg 122: 438-448, 2008. [PDF]
63)* Kurita M, Kato H, Yoshimura K. A therapeutic strategy based on histological assessment of hyperpigmented skin lesions in Asians. J Plast Reconstr Aesthe Surg 62: 955-963, 2009. [PDF]
64)* Yoshimura K, Aoi N, Suga H, Inoue K, Eto H, Sato K, Kurita M, Harii K, Hirohi T. Ectopic fibrogenesis induced by transplantation of adipose-derived progenitor cellsuspension immediately after lipoinjection. Transplantation 85: 1868-1869, 2008. [PDF]
65)* Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, Nishimura S, Manabe I, Gonda K, Yoshimura K. FGF-2-induced HGF secretion by adipose-derived stromal cells inhibits post-injury fibrogenesis through a JNK-dependent mechanism. Stem Cells 27: 238-249, 2009. [PDF]
66)* Yoshimura K, Asano Y, Aoi N, Kurita M, Oshima Y, Sato K, Inoue K, Suga H, Eto H, Kato H, Hirohi T, Harii K. Progenitor-enriched adipose tissue transplantation as rescue for breast implant complications. Breast J 16: 169-175, 2010 [PDF]
67)* Inoue K, Kato H, Sato T, Osada A, Aoi N, Suga H, Eto H, Gonda K, Yoshimura K. Evaluation animal models for the hair inducing capacity of cultured human dermal papilla cells. Cell Tissue Organ 190: 102-110, 2009. [PDF]
68)* Yoshimura K, Sato K, Matsumoto D. Cell-assisted lipotransfer for breast augmentation: grafting of progenitor-enriched fat tissue. In Autologous fat transplantation (Ed by Shiffman MA), Marcel Dekker, Inc., New York, pp261-271, 2010. [PDF]
69)* Yoshimura K, Suga H, Eto H. Adipose-derived stem/progenitor cells: roles in adipose tissue remodeling and potential use for soft tissue augmentation. Regen Med 4: 265-73, 2009. [PDF]
70)* Yoshimura K, Asano Y. Fat injection to the breasts: cosmetic augmentation, implant replacement, inborn deformity, and reconstruction after mastectomy. In Aesthetic and Reconstructive Surgery of the Breast (Eds) Hall-Findlay EJ, Evans GRD., Elsevier Ltd, London, in press. [proofPDF]
71)* Inoue K, Aoi N, Yamauchi Y, Sato T, Suga H, Eto H, Kato H, Tabata Y, Yoshimura K. TGF-β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis, J Cell Mol Med 13: 4643-4656, 2009.[PDF]
72)* Suga H, Araki J, Aoi N, Kato H, Higashino T, Yoshimura K. Adipose tissue remodeling in lipedema: adipocyte death and concurrent regeneration. J Cutan Pathol 36: 1293-1298, 2009. [PDF]
73)* Suga H, Matsumoto D, Shigeura T, Eto H, Inoue K, Aoi N, Kato H, Araki J, Yoshimura K. Functional implications of CD34 expression in human adipose-derived stem/progenitor cells. Stem Cell Dev 18: 1201-1209, 2009. [PDF]
74)* Yoshimura K. Clinical use of adipose-derived stem cells for breast volume enhancement. ISAPS News 2(3), 6-9, 2008. [PDF]
75) Hirohi T, Yoshimura K. Lower face reduction with full-thickness marginal ostectomy of mandibular corpus-angle followed by corticectomy. J Plast Reconstr Aesthe Surg, in press.
76)* Aoi N, Yoshimura K, Kadono T, Nakagami G, Iizuka S, Higashino T, Araki J, Koshima I, Sanada H. Ultrasound assessment of deep tissue injury in pressure ulcers: possible prediction of pressure ulcer progression. Plast Recosntr Surg 124: 540-550, 2009. [PDF]
77)* Eto H, Suga H, Matsumoto D, Shigeura T, Inoue K, Aoi N, Kato H, Araki J, Yoshimura K. Characterization of adipose tissue structure and cellular components: Differences between aspirated adipose tissue and excised adipose tissue. Plast Reconstr Surg 124: 1087-1097, 2009. [PDF]
78)* Suga H, Eto H, Inoue K, Aoi N, Kato H, Araki J, Higashino T, Yoshimura K. Cellular and molecular features of lipoma tissue: comparison with normal adipose tissue. Br J Dermatol 161: 819-825, 2009. [PDF]
79)* Inoue K, Aoi N, Sato T, Yamauchi Y, Suga H, Eto H, Kato H, Araki J, Yoshimura K. Differential expression of stem cell-associated markers in human hair follicle epithelial cells. Lab Invest , Lab Invest 89: 844-56, 2009. [PDF]
80) Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R, CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 15: 914-920, 2009. [PDF]
81)* Kato H, Yoshida R, Tsukamoto K, Suga H, Eto H, Higashino T, Araki J, Ogata T, Yoshimura K. Familial cases with atypical clinical features genetically diagnosed as multiple lentigines syndrome (LEOPARD syndrome). Int J Dermatol, in press.
82)* Kato H, Suga H, Eto H, Aoi N, Araki J, Doi K, Higashino T, Iida T, Tabata Y, Yoshimura K. Reversible adipose tissue enlargement induced by external tissue suspension: possible contribution of basic fibroblast growth factor for preservation of enlarged tissue. Tissue Eng Part A 16: 2029-2040, 2010. [PDF]
83)* Aoi N, Inoue K, Kato H, Suga H, Eto H, Doi K, Iida T, Yoshimura K. Clinically applicable transplantation of dermal papilla cell construct for hair follicle regeneration. J Tissue Eng Reg Med 6: 85-95, 2012. [PDF]
84)* Suga H, Eto H, Aoi N, Kato H, Araki J, Doi K, Yoshimura K. Adipose tissue remodeling under ischemia: Death of adipocytes and activation of stem/progenitor cells. Plast Reconstr Surg 126: 1911-1923, 2010. [PDF]
85)* Eto H, Suga H, Aoi N, Kato H, Araki J, Doi K, Yoshimura K. Adipose injury-associated factors activate adipose stem/stromal cells, induce neoangiogenesis, and mitigate hypoxia in ischemic tissues. Am J Pathol 178: 2322-2332, 2011. [PDF]
86)* Kurita M, Matsumoto D, Kato H, Araki J, Higashino T, Fujino T, Takasu K, Yoshimura K. Tissue reactions to cog structure and pure gold in lifting threads: A histological study in rats. Aesthe Surg J 31: 347-351, 2011. [PDF]
87) Hirohi T, Yoshimura K. Vertical enlargement of palpebral aperture by static shortening of the anterior and posterior lamella of the lower eyelid; a cosmetic option for Asian eyelids. Plast Reconstr Surg 127: 396-406, 2011. [PDF].
88)* Kato H, Araki J, Eto H, Doi K, Hirai R, Kuno S, Higashino T, Yoshimura K. A prospective randomized controlled study of oral tranexamic acid for preventing post-inflammatory hyperpigmentation after Q-switched ruby laser. Derm Surg 37: 605-610, 2011. [PDF]
89) Minematsu T, Huang L, Ibuki A, Nakagami G, Akase T, Sugama J, Nagase T, Yoshimura K, Sanada H. Altered expression of matrix metalloproteinases and their tissue inhibitors in matured rat adipocytes in vitro. Biol Res Nurs, in press.
90) Zhang X, Hirai M, Cantero S, Ciubotariu R, Dobrila L, Hirsh A, Igura K, Satoh H, Yokomi I, Nishimura T, Yamaguchi S, Yoshimura K, Rubinstein P, Takahashi TA. Isolation of human umbilical cord blood derived mesenchymal stem cells: Quantitation of increased cellular viability at shorter times after delivery and high ability to proliferate and differentiate to chondrocytes as compared to mesenchymal stem cells from bone marrow and adipose tissue. J Cell Biochem  112: 1206-1218, 2011.
91) Chazenbalk G, Bertolotto C, Heneidi S, Aronowitz J, Yoshimura K, Simmons CF, Azziz R. Novel pathway of adipogensis through cross-talk between adipose tissue macrophages, adipose stem/progenitor cells and adipocytes. Plos One 6: e17834, 2011. [PDF]
92) Gimble JM, Bunnell BA, Casteilla L, Jung JS, Yoshimura K. Phases I–III clinical trials using adult stem cells. Stem Cells Int 2010: 604713, 2011.
93) Minematsu T, Yamamoto Y, Nagase T, Naito A, Takehara K, Iizuka S, Komagata K, Huang L, Nakagami G, Akase T, Oe M, Yoshimura K, Ishizuka T, Sugama J, Sanada H. Aging enhances maceration-induced ultrastructural alteration of the epidermis and impairment of skin barrier function. J Dermatol Sci 62: 160-168, 2011. [PDF]
94) Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M, Awazawa M, Kobayashi M, Sasako T, Kaneko K, Suzuki M, Nishikawa Y, Hara K, Yoshimura K, Koshima I, Goyama S, Murakami K, Sasaki J, Nagai R, Kurokawa M, Sasaki T, Kadowaki T. Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance. Proc Natl Acad Sci U S A 108: 5753-5758.
95)* Eto H, Suga H, Aoi N, Kato H, Doi K, Kuno S, Tabata Y, Yoshimura K. Therapeutic potential of fibroblast growth factor-2 for hypertrophic scars: upregulation of MMP-1 and HGF expression. Lab Invest 92: 214 – 223. [PDF]
96)* Yoshimura K, Eto H, Kato H, Doi K, Kuno S, Aoi N. In vivo manipulation of stem cells for adipose tissue repair/reconstruction. Reg Med 6(6 Suppl.): 33–41, 2011. [PDF]
97) Ohto-Fujita E, Konno T, Shimizu M, Ishihara K, Sugitate T, Miyake J, Yoshimura K, Taniwaki K, Sakurai T, Hasebe Y, Atomi Y. Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts. Cell Tissue Res 345: 177-190, 2011. [PDF]
98) Goisis M, Yoshimura K, Heden P. Breast Augmentation After Macrolane Filler Injections. Aesth Plast Surg, DOI 10.1007/s00266-011-9763-3
99)* Araki J, Jona M, Eto H, Aoi N, Kato H, Suga H, Doi K, Yatomi Y, Yoshimura K. Optimized preparation method of platelet-concentrated plasma (PCP) and non-coagulating platelet-derived factor concentrates (PFC): Maximization of platelet concentration and removal of fibrinogen. Tissue Eng part C, in press.[PDF]
100)* Yoshimura K. From Liposuction to adipose tissue engineering. In: Drs. Illouz Yves Gerard and Sterodimas Aris, eds. Adipose Stem Cells and Regenerative Medicine. Springer, Heiderberg, Germany, in press.
101)* Yoshimura K, Asano Y, Aoi N, Eto H, Doi K, Kato H. Minimal Scar Breast Augmentation Using Autologous Fat Grafting, Body In: Contouring and Liposuction, edited by Rubin JP, Jewell M, Richter D, and Uebel C, Elsevier, London, UK, in press.

 102) Asada M, Nakagami G, Minematsu T, Nagase T, Akase, T, Huang L, Yoshimura K, Sanada H. Novel biomarkers for the detection of wound infection by wound fluid RT-PCR in rats. J Dermatol Sci 21: 118-122, 2012.
103)* Eto H, Kato H, Suga H, Aoi N, Doi K, Kuno S, Yoshimura K. The fate of adipocytes after non-vascularized fat grafting: Evidence of early death and replacement of adipocytes. Plast Reconstr Surg 129: 1081-1092, 2012.
104) Ibuki A, Akase T, Nagase T, Minematsu T, Nakagami G, Horii M, Sagara, H, Komeda T, Kobayashi M, Shimada T, Aburada M, Yoshimura K, Sugama J, Sanada H. Skin fragility in obese diabetic mice: possible involvement of elevated oxidative stress and upregulation of matrix metalloproteinases. Exp Dermatol 21: 178-183, 2012..
105) Rubin JP, O’Brien DC, Zuley M, Toy J, Asano Y, Kurita M, Aoi N, Harii K, Yoshimura K. Mammographic changes after fat transfer to the breast compared with changes after breast reduction: a blinded study. Plast Reconstr Surg 129: 1029-1038, 2012.
106) Doi K, Tanaka S, Iida H, Eto H, Kato H, Aoi N, Kuno S, Hirohi T, Yoshimura K. Stromal vascular fraction isolated from lipoaspirates using an automated processing system: bench and bed analysis. J Tissue Eng Reg Med, in press. doi: 10.1002/term.1478.
107) Asada M, Nakagami G, Minematsu T, Nagase T, Akase T, Huang L, Yoshimura K, Sanada H. Novel models for bacterial colonization and infection of full-thickness wounds in rats. Wound Repair Regen, in press. doi: 10.1111/j.1524-475X.2012.00800.x.
108) Aoi N, Inoue K, Chikanishi T, Fujiki R, Yamamoto H, Kato H, Eto H, Doi K, Itami S, Kato S, Yoshimura K. 1α,25-dihydroxyvitamin D3 modulates the hair-inductive capacity of dermal papilla cells: Therapeutic potential for hair regeneration. Stem Cells Transl Med, in press.